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ADHD Medications

Intuniv for ADHD: Metabolic Challenges

by Dr Charles Parker on February 1, 2010 · 23 comments

Burn Rate Explained

Intuniv, As With Any ADHD Medications: Watch the Burn Rate

Intuniv Posts:
This post is the fifth, with four others, documenting Intuniv Overview, Dosing Details, Drug Interactions and Addiction Indications. Please review all of these posts and the many comments [over 150] on the Overview post to see what readers are saying about Intuniv, this interesting new ADHD non-stimulant medication.

Burn Rate:
If you have been reading CorePsych Blog you will note that I have been writing about my new book, – and the good news, it’s finished, and in edit at this moment – I do hope to get it out by March ‘10. The Patient’s Guide for ADHD Medications: What To Do When Nothing Is Working details an entire chapter on Burn Rate, as everyone who takes ADHD meds should absolutely master the burn rate principle.

This Specific Q & A:
- Is an example of the many Intuniv questions, challenges and positive remarks in these several posts:

Question About 8 yo Boy, Picky Eater and Metabolic Challenges:
“I have just stumbled across you and this site in my research into Intuniv. My son just recently turned 8 and was diagnosed with ADHD this past spring. As I continually read about ADHD kids Luke seems wise beyond his years, is very bright when it comes to building things, or math, and picks things up quickly when he is receiving instruction one on one or in a very small group,- but he struggles in school generally. Long story short, we started with a Central Auditory Processing Disorder diagnosis when he was six.  His primary issue seemed to be language, both receptive and expressive. An exam with an audiologist confirmed a fairly significant CAPD at the time. As he progressed in school it was obvious that ADHD was also a large part of his problems as impulsivity, restlessness, inability to attend, and defiance increased as he got older. We saw a neurologist who, after an EEG, prescribed Focalin XR. This worked like MAGIC, at first.

We started with 5mg and after about a month moved up to 10mg. He was able to focus, concentrate and made great strides in school. His language issues even seemed to improve. Now it seems the Focalin is either failing him or is the wrong drug. His ability to focus has tanked, he has become very impulsive (throwing things, slamming things on his desk) and is increasingly defiant (refuses to do work, follow directions). While other times he seems spaced out, and at home sometimes too compliant, and sometimes melancholy for no reason. With age it seems his receptive language abilities are about right, and at developmental level, but his expressive abilities are still below, which of course is leading to some frustration on his part especially when he is supposed to expressing himself through writing. We were seen by the NP in the neurologist’s office today and she suggested Intuniv. From what I’m reading it sounds like it may work for Luke but she has suggested we stay on the Focalin while we start the Intuniv? Do you agree? (She mentioned d/c’ing the Focalin eventually)

Second, in one of the posts above you mentioned something about “immune dysfunction, bowel challenges and is-he-a-picky-eater”. While Luke is rarely sick, I don’t think he has a solid BM in his life (not watery, but always very, very soft) and he would live on Mac and cheese, peanut butter and jelly and chips if I’d let him. He NEVER willingly tries anything new and is indeed very picky about what he eats. As all of this is very new to me can you shed some light on what this may have to do with anything and what to do about it – or point me to the best place to read about it? We have tried adjusting his diet, etc. in the past but because he is so picky it is very difficult to do.

An Additional Metabolic Point - Headaches
One additional thing that the NP this a.m. more or less ignored – prior to starting meds Luke would wake up in the middle of the night crying and saying his head hurt. He’d be up 30 min. or more, would eventually throw up and then go back to sleep. In the morning you’d never know anything happened. This would happen about once a month from the time he was about 6. I only recall it happening once during the day at school. Once we started Focalin those incidents ceased completely. We had our first return of that 2 nights ago. Any idea what that’s all about? Initially the neurologist said it was “interesting”but had little else to say about it.”

My Answer, Abbreviated To Stay With Metabolism and Burn Rate:
My reaction to this question and many others seen on the many comments on Intuniv and Vyvanse: We must always look at the metabolic hints, the possible changes in metabolic rate before starting the meds. They are subtle but include the following:
- History of bowel issues, too soft, too hard, constipation, diarrhea, monolithic stools, too slow in transit time,
- Developmental delay issues: CAPD, speech issues, Asperger’s, Autism,
- History of Fetal Alcohol exposure
- Headaches, stomach aches, tired all of the time, dark circles under the eyes, pale skin
- Picky Eater
- Not eating breakfast, waking with stomach issues and no appetite
- History of failure with many meds – including stimulants or non-stimulants [Intuniv, Strattera]
- Narrow Therapeutic Window
- History of food allergies even back to early childhood, e.g. “lactose intolerance”
- History of rashes, allergies, asthma, upper respiratory infections, ear infections

If we don’t look at these issues [and more] we cannot predict what the outcome with the medications will be – and every one of these issues can significantly change the underlying metabolic patterns, the amount of neurotransmitters in the body, and the cofactors that burn the neurotransmitters effectively.

Medication management now requires a full awareness of the entire pattern including nutrition [which feeds the amino acid building blocks for neurotransmitters and cofactors], – without more careful questioning at the outset we will have predictable problems – as the burn rate will vary dramatically with all of these variables. Burn rate will effect Duration of Effectiveness [DOE] – dosage patterns and speed of titration at the onset of meds.

Then, if Burn Rate varies, we must always take the next step to measure the immune dysregulations, the neurotransmitters, and the downstream endocrine issues so often found with these upstream irregularities.

Phone Consult Availability
Check out these remarks regarding how to start these reviews with a phone consult: See this post on Intuniv: Comment by Gina Pera on January 29, ‘10 2:30 PM

—>Tweet this post below! For ADHD Medications: Download complimentary white paper Precise Solutions now, – and get ready for the complete version of ‘The Patient’s Guide’ details to follow. Get Neurotransmitter Details Here

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Holistic Psychiatry is CorePsych

by Dr Charles Parker on January 4, 2010 · 5 comments

colossal

A New View: gato-gato-gato via Flickr

The Core of Psychiatry is Changing – Neuroscience Evidence Changes Thinking

We’ve been talking about the evolution of psychiatry here at CorePsych Blog for more than 3 years – and you know from these pages that mind progress has been dramatic. From SPECT brain imaging, to NeuroScience testing, the new technology provides distinctive different ways to understand old problems.

This January 26 & 27, just a few weeks away, you will have an opportunity to take a deeper step into that change process: The Holistic Health Virtual Conference: Empowering Whole People – I hope you can join me there.

This Holistic Health conference introduces a different view for the new year: Science applied to Health: mind and body connections – all hooked up with evidence that works in everyday life – from some of the most respected national thought leaders.

Hosted by the quick and effervescent Jennifer Koretsky, the conference will have that same here-is-what-to-do-next, bottom line, street-smart focus on applications, not theory. Jennifer hosted the Virtual AD/HD Conference last year, and is the author of Odd One Out: The Mavericks Guide to Adult ADD, and brings an easy-listening experience to her conferences.

Join me with other esteemed colleagues:

- Notably: Daniel Amen MD: Pioneer in brain imaging evidence – has written 23 books, has appeared on PBS regularly, and is a national thought leader in psychiatry who has significantly changed our outlook on the use of brain evidence in everyday office practice. I had the privilege of working with Daniel for 4 years, starting in 2003 with our opening of Amen Clinic DC, in Reston, VA, – and can report without reservation that the tour with him up there significantly changed my professional life – my practice of psychiatry. When you hear his presentation, you will agree, he is one of the very best speakers out there. Engaging, witty, humorous and practical, he will be talking about mind body connections and will definitely get you thinking about evidence that works.

- And check out these other folks on Vit D3, Toxins, Bioidentical Hormones, Food as Medicine: On this Agenda Page at Holistic Health

- My presentation: So much of our current health delivery system in psychiatry is limited only to the best in psychopharmacology – and directed to illness in the moment. Frequently, speaking from my own past experience, we have limited our view to the synapse, as the only tools we have used are medications that hit those brain synaptic connections. With new tools, new evidence, and new thinking, we now have a much more comprehensive way to measure brain health.We are rapidly moving from macro to micro in our new assessment strategies. I will summarize what you need to know to get started. Bottom line: Comprehensive thinking beats categorical thinking every time.

The challenge: How to put all the evidence together for your comprehensive care, and for comprehensive self care. My presentation will take you into the molecular and cellular measurements now available to understand immune, hormone and neurotransmitter assessments – without tying you down with jargon. These new measurement tools are readily available, are often quite cost effective, and will tell you volumes about your brain and body connections and, as mentioned above: what -to-do- next.

It won’t matter who you are, public or professional, you need to hear this information to effectively practice 21st century health medicine, 21st century self care. Start the New Year right: Holistic Health Conference.

Hope to see you there, and do retweet this below if you think your followers might be interested in the real deal. ;-)
Talk soon,
cp

—>Tweet this post below! For ADHD Medications: Download complimentary white paper Precise Solutions now, – and get ready for the complete version of ‘The Patient’s Guide’ details to follow. Get Neurotransmitter Details Here

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Intuniv for ADHD: Avoid Drug Interactions

December 16, 2009 Beyond ADHD

Intuniv Driving And Watching: Possible Interactions Detailed – Regular CorePsych Blog readers already know that we don’t like wrong medication turns. Intuniv dosing is important. Intuniv safety has been carefully explored. Maps do help, but watching where we are going is even better.

33 comments Read the full article here →

Intuniv For ADHD: Dosing Details

November 28, 2009 Autism Spectrum

Intuniv For ADHD Is Guanfacine, But Better and Easier – ADHD treatment evolves: This will be a short note to quickly address the growing comments here at CorePsych Blog on the previous Intuniv post.

96 comments Read the full article here →

Virtual ADHD Conf Starts Monday

October 3, 2009 Beyond ADHD

Pay Attention to ADHD Meds, Go ahead and give yourself a present that you can use all year! Now you can get all the tools you need to succeed with ADHD

3 comments Read the full article here →

ADHD Experts: Convenient, Latest ADHD Insights

September 19, 2009 Beyond ADHD

Can’t Make That National ADHD Meeting? – Bring It To Your Home – And the best news: attend live, or attend through the year – anytime you want. National experts on MP3 for that ride to work! The best advantage: great speakers, the latest insights, lowest cost, available for replay.

4 comments Read the full article here →

Impulsivity Translated for Street Applications: The Impulsive Brain

September 13, 2009 Beyond ADHD

Impulsivity is, without doubt, the most frequent challenge in our daily lives – for mental health professionals, teachers, HR professionals, physicians, and anyone working with administrative challenges. Let’s call it a problem instead of rationalizing the behavior-

0 comments Read the full article here →

Vyvanse Adjustments: Start By Looking for the Exact Window

September 6, 2009 Beyond ADHD

Watch For: Top of the Therapeutic Window -This comment on Vyvanse is worth your time, and is so commonly seen in the office. Vyvanse in the PM is so forgiving – that when it finishes, it is hard to assess. Measure the DOE anyway – start with that process.

21 comments Read the full article here →

Brain News: CorePsych Radio Availability

August 6, 2009 Beyond ADHD

Increased Availability with CorePsych Radio Programs- Heads up for many more CorePsych Radio program choices

3 comments Read the full article here →

Vyvanse for ADHD: The Complete Story on CorePsych Radio

June 18, 2009 Beyond ADHD

Vyvanse Works Exceedingly Well If You Know How to Work It – Vyvanse continues to prove itself as the most effective ADHD stimulant ever – but many still simply don’t know how to use it.

6 comments Read the full article here →